Seminars in Thoracic and Cardiovascular Surgery
Volume 21, Issue 2 , Pages 159-163 , Summer 2009

Radiation Therapy Options for Malignant Pleural Mesothelioma

  • Elizabeth H. Baldini, MD, MPH

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Elizabeth H. Baldini, MD, MPH, Department of Radiation Oncology, Dana-Farber/Brigham and Women's Hospital Cancer Center, 75 Francis Street, Boston, MA 02115

References 

  1. Enami BE, Lyman J, Brown A, et al. Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys. 1991;21:109–122
  2. Alberts AS, Falkson F, Goedhals L, et al. Malignant pleural mesothelioma: A disease unaffected by current therapeutic measures. J Clin Oncol. 1988;6:527–535
  3. Ball DL, Cruickshank DG. The treatment of malignant mesothelioma of the pleura: Review of a 5-year experience, with special reference to radiotherapy. Am J Clin Oncol. 1990;13:4–9
  4. Maasilta P. Deterioration in lung function following hemithorax irradiation for pleural mesothelioma. Int J Radiat Oncol Biol Phys. 1991;20:433–438
  5. Munter MW, Christian T, Nikoghosyan A, et al. Inverse planned stereotactic intensity modulated radiotherapy (IMRT) in the palliative treatment of malignant mesothelioma of the pleura: The Heidelberg experience. Lung Cancer. 2005;49S1:S83–S86
  6. Hilaris BS, Nori D, Kwong E, et al. Pleurectomy and intraoperative brachytherapy and postoperative radiation in the treatment of malignant pleural mesothelioma. Int J Radiat Oncol Biol Phys. 1984;10:325–331
  7. Kutcher GJ, Kestler C, Greenblat D, et al. Technique for external beam treatment for mesothelioma. Int J Radiat Oncol Biol Phys. 1987;13:1747–1752
  8. Gupta V, Mychalczak B, Krug L, et al. Hemithoracic radiation therapy after pleurectomy/decortication for malignant pleural mesothelioma. Int J Radiat Oncol Biol Phys. 2005;63:1045–1052
  9. Achatzy R, Beba W, Ritschler R, et al. The diagnosis, therapy and prognosis of diffuse malignant mesothelioma. Eur J Cardiothorac Surg. 1989;3:445–448
  10. Soysal O, Karaoglanoglu N, Demircan S, et al. Pleurectomy/decortication for palliation in malignant pleural mesothelioma: Results of surgery. Eur J Cardiothorac Surg. 1997;11:210–213
  11. Lee TT, Everett DL, Shu HKG, et al. Radical pleurectomy/decortication and intraoperative radiotherapy followed by conformal radiation with or without chemotherapy for malignant pleural mesothelioma. J Thorac Cadiovasc Surg. 2002;124:1183–1189
  12. Tobler M, Watson G, Leavitt DD. Intensity-modulated photon arc therapy for treatment of pleural mesothelioma. Med Dosim. 2002;27:255–259
  13. Rosenzweig KE, Laser B, Krug L, et al: Pleural intensity modulated radiation therapy in patients with malignant pleural mesothelioma: Proceedings of the 9th International Conference of the International Mesothelioma Interest Group, p 51, 2008
  14. Baldini EH, Recht A, Strauss GM, et al. Patterns of failure after trimodality therapy for malignant pleural mesothelioma. Ann Thorac Surg. 1997;63:334–338
  15. Allen AM, Den R, Wong JS, et al. Influence of radiotherapy technique and dose on patterns of failure for mesothelioma patients after extrapleural pneumonectomy. Int J Radiat Oncol Biol Phys. 2007;68:1366–1374
  16. Yajnik S, Rosenzweig KE, Mychalczak B, et al. Hemithoracic radiation after extrapleural pneumonectomy for malignant pleural mesothelioma. Int J Radiat Oncol Biol Phys. 2003;56:1319–1326
  17. Rusch VW, Rosenzweig K, Venkatraman E, et al. A phase ii trial of surgical resection and adjuvant high-dose hemithoracic radiation for malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2001;122:788–795
  18. Flores RM, Krug LM, Rosenzweig KE, et al. Induction chemotherapy, extrapleural pneumonectomy, and post-operative high-dose radiotherapy for locally advanced malignant pleural mesothelioma: A phase II trial. J Thorac Oncol. 2006;1:289–295
  19. Rea F, Mrulli G, Bortolotti L, et al. Induction chemotherapy, extrapleural pneumonectomy (EPP) and adjuvant hemi-thoracic radiation in malignant pleural mesothelioma (MPM): Feasibility and results. Lung Cancer. 2007;57:89–95
  20. Ahamad A, Stevens CW, Smythe WR, et al. Intensity-modulated radiation therapy: A novel approach to the management of malignant pleural mesothelioma. Int J Radiat Oncol Biol Phys. 2003;55:768–775
  21. Forster KM, Smythe WR, Starkschall G, et al. Intensity-modulated radiation therapy following extrapleural pneumonectomy for the treatment of malignant mesothelioma: Clinical implementation. Int J Radiat Oncol Biol Phys. 2003;55:606–616
  22. Rice DC, Stevens CW, Correa AM, et al. Outcomes after extrapleural pneumonectomy and intensity-modulated radiation therapy for malignant pleural mesothelioma. Ann Thorac Surg. 2007;84:1685–1693
  23. Miles EF, Larrier NA, Kelsey CR, et al. Intensity-modulated radiotherapy for resected mesothelioma: The Duke experience. Int J Radiat Oncol Biol Phys. 2008;71:1143–1150
  24. Krayenbuehl J, Oertel S, Davis JB, et al. Combined photon and electron three-dimensional conformal versus intensity modulated radiotherapy with integrated boost for adjuvant treatment of malignant pleural mesothelioma after pleuropneumonectomy. Int J Radiat Oncol Biol Phys. 2007;69:1593–1599
  25. Allen AM, Czerminska M, Janne P, et al. Fatal pneumonitis associated with intensity-modulated radiation therapy for mesothelioma. Int J Radiat Oncol Biol Phys. 2006;65:640–645
  26. Allen AM, Schofield D, Hacker F, et al. Restricted field IMRT dramatically enhances IMRT planning for mesothelioma. Int J Radiat Oncol Biol Phys. 2007;69:1587–1592
  27. Rice DC, Smythe WR, Liao Z, et al. Dose-dependent pulmonary toxicity after postoperative intensity-modulated radiotherapy for malignant pleural mesothelioma. Int J Radiat Oncol Biol Phys. 2007;69:350–357
  28. Sterzing F, Sroka-Perez G, Schubert K, et al. Evaluating target coverage and normal tissue sparing in the adjuvant radiotherapy of malignant pleural mesothelioma: Helical tomotherapy compared with step-and-shoot IMRT. Radiother Oncol. 2008;86:251–257
  29. Chan MF, Chui CS, Song Y, et al. A novel radiation therapy technique for malignant pleural mesothelioma combining electrons and intensity-modulated photons. Radiother Oncol. 2006;79:218–223
  30. Bjelkengren G, Glimelius B. The potential of proton beam radiation therapy in lung cancer (including mesothelioma). Acta Oncol. 2005;44:881–883
  31. Xia H, Karasawa K, Hanyu N, et al. Hyperthermia combined with intra-thoracic chemotherapy and radiotherapy for malignant pleural mesothelioma. Int J Hyperthermia. 2006;22:613–621
  32. Suzuki M, Endo K, Satoh H, et al. A novel concept of treatment of diffuse or multiple pleural tumors by boron neutron capture therapy (BNCT). Radiother Oncol. 2008;88:192–195
  33. Gordon W, Antman KH, Greenberger JS, et al. Radiation therapy in the management of patients with mesothelioma. Int J Radiat Oncol Biol Phys. 1982;8:19–25
  34. Davis SR, Tan L, Ball DL. Radiotherapy in the treatment of malignant mesothelioma of the pleura, with special reference to its use in palliation. Australas Radiol. 1994;38:212–214
  35. De Graaf-Strukowska L, Van Der Zee J, van Putten W, et al. Factors influencing the outcome of radiotherapy in malignant mesothelioma of the pleura-a single institution experience with 189 patients. Int J Radiat Oncol Biol Phys. 1999;43:511–516

PII: S1043-0679(09)00073-2

doi: 10.1053/j.semtcvs.2009.06.009

Seminars in Thoracic and Cardiovascular Surgery
Volume 21, Issue 2 , Pages 159-163 , Summer 2009

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