Sentinel Node and Positron Emission Tomography Mapping in Lung Cancer
Radioguided lymph node mapping can potentially improve staging in locoregional non-small cell lung cancer. This is accomplished by using advanced pathologic techniques to detect micrometastases in selected thoracic lymph nodes. The use of isosulfan blue, technetium-99m and 18F-fluorodeoxyglucose (FDG) as mapping agents have been reported. Despite several limitations in this technique, it may facilitate the selection of patients for novel therapies, resulting in improved outcomes for lung cancer patients.
Department of Surgery, University at Buffalo, SUNY; Department of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, New York
Address reprint requests to Chukwumere Nwogu, MD, Department of Thoracic Surgery, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263