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Commentary: Considering Treating Postoperative Atrial Fibrillation With Direct Oral Anticoagulants

      The evolving reputation of dual oral anticoagulants in treating patients with postoperative atrial fibrillation depends on safety, effect on long-term outcome and cost-effectiveness of the medication.
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      Linked Article

      • Safety of Direct Oral Anticoagulants Compared to Warfarin for Atrial Fibrillation after Cardiac Surgery: A Systematic Review and Meta-Analysis
        Seminars in Thoracic and Cardiovascular SurgeryVol. 34Issue 3
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          The evidence for use of direct oral anticoagulants (DOACs) in the management of post-operative cardiac surgery atrial fibrillation is limited and mostly founded on clinical trials that excluded this patient population. We performed a systematic review and meta-analysis of clinical trials and observational studies to evaluate the hypothesis that DOACs are safe compared to warfarin for the anticoagulation of patients with post-operative cardiac surgery atrial fibrillation. We searched PubMed, EMBASE, Web of Science, clinicaltrials.gov, and the Cochrane Library for clinical trials and observational studies comparing DOAC with warfarin in patients ≥18 years old who had post-cardiac surgery atrial fibrillation.
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