Commentary: Is It Time to Change Management Guidelines and Referral Patterns for PE?

      Surgical embolectomy and VA ECMO are important salvage strategies for massive PE. Early referral to centers equipped with surgical and ECMO expertise could substantially improve outcome.
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        • Secemsky E.
        • Chang Y.
        • Jain C.C.
        • et al.
        Contemporary management and outcomes of patients with massive and submassive pulmonary embolism.
        Am J Med. 2018; 131: 1506-1514
        • Jaff M.
        • McMurtry S.
        • Stephen A.
        • et al.
        Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension.
        Circulation. 2011; 126: 1788-1830
        • Goldberg J.B.
        • Spevak D.M.
        • Ahsan S.
        • et al.
        Comparison of surgical embolectomy and veno-arterial extracorporeal membrane oxygenation for massive pulmonary embolism.
        Semin Thorac Cardiovasc Surg. 2022; 34: 934-942
        • Minakawa M.
        • Fukuda I.
        • Miyata H.
        • et al.
        Outcomes of pulmonary embolectomy for acute pulmonary embolism.
        Circulation. 2018; : 2184-2190

      Linked Article

      • Comparison of Surgical Embolectomy and Veno-arterial Extracorporeal Membrane Oxygenation for Massive Pulmonary Embolism
        Seminars in Thoracic and Cardiovascular SurgeryVol. 34Issue 3
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          Massive pulmonary embolism (MPE) is associated with a 20-50% mortality rate with guideline directed therapy. MPE treatment with surgical embolectomy (SE) or venoarterial extracorporeal membrane oxygenation (VA-ECMO) have shown promising results. In the context of a surgical management strategy for MPE, a comparison of outcomes associated with VA-ECMO or SE was performed. A retrospective review of a single institution cardiac surgery database was performed, identifying MPE treated with SE or VA-ECMO between 2005-2020.
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