ADULT – Commentary| Volume 34, ISSUE 3, P878-879, September 2022

Commentary: The Shrinking Role of the Freestyle Aortic Bioprostheses in Younger Patients

  • Leora B. Balsam
    Address reprint requests to Leora B. Balsam, MD, Division of Cardiac Surgery, UMass Memorial Medical Center, University Campus, 55 Lake Avenue North, Worcester, MA 01655.
    Division of Cardiac Surgery, UMass Memorial Medical Center, Worcester, Massachusetts
    Search for articles by this author
Published:September 06, 2021DOI:
      Should the Freestyle aortic bioprosthesis be implanted in younger patients? Outcomes of a new study call this practice into question.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Seminars in Thoracic and Cardiovascular Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Khazaal J.
        • Ragagni M.
        • Parker J.
        • et al.
        Freestyle aortic bioprostheses in patients 60 years old and younger.
        Sem Thorac Cardiovasc Surg. 2022; 34: 870-877
        • Yang B.
        • Patel H.J.
        • Norton E.L.
        • et al.
        Aortic valve reoperation following stentless bioprosthesis: Short- and long-term outcomes.
        Ann Thorac Surg. 2018; 106: 521-525
        • Otto C.M.
        • Nishimura R.A.
        • Bonow R.O.
        • et al.
        2020 ACC/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines.
        Circulation. 2021; 143: e72-227
        • Bach D.S.
        • Kon N.D.
        Long-term clinical outcomes 15 years after aortic valve replacement with the freestyle stentless aortic bioprosthesis.
        Ann Thorac Surg. 2014; 97: 544-551
        • Une D.
        • Karkhanis R.
        • David T.E.
        • et al.
        Long-term clinical outcomes of the Toronto stentless porcine valve: 15-year results from dual centers.
        J Card Surg. 2020; 35: 2279-2285
        • Yang B.
        • Malik A.
        • Farhat L.
        • et al.
        Influence of age on longevity of a stentless artic valve.
        Ann Thorac Surg. 2020; 110: 500-507

      Linked Article

      • Freestyle Aortic Bioprostheses in Patients 60 Years old and Younger
        Seminars in Thoracic and Cardiovascular SurgeryVol. 34Issue 3
        • Preview
          Evaluate outcomes of the Freestyle stentless aortic bioprosthesis in patients 60 years old and younger. All patients, 60 years old and younger, between January 1, 1998 to December 31, 2015 who underwent implantation of a Freestyle aortic valve at a single institution were reviewed. Medical records and telephone interviews were utilized for data collection. 515 patients were identified with an average age of 51.3 years. Mean follow up was 11.1 years. 225 full root replacements and 290 subcoronary implants were performed.
        • Full-Text
        • PDF