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Commentary: Concomitant LAA Closure; A No-Brainer to Protect the Brain?

  • Patrick M. McCarthy
    Correspondence
    Address reprint requests to Patrick M. McCarthy, MD, Northwestern Medical Group, Chief of the Cardiac Surgery Division, Division of Cardiac Surgery, Heller-Sacks Professor of Surgery at the Northwestern University Feinberg School of Medicine, Northwestern University, 676 North Saint Clair St, Arkes Family Pavilion, Suite 730, Chicago, Illinois 60611.
    Affiliations
    Division of Cardiac Surgery, Department of Surgery, Northwestern Medicine, Northwestern University, Chicago, Illinois.
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  • Jane Kruse
    Affiliations
    Division of Cardiac Surgery, Department of Surgery, Northwestern Medicine, Northwestern University, Chicago, Illinois.
    Search for articles by this author
      The data to support closure of the LAA in patients with AF undergoing cardiac surgery is very strong. The next study of LAA closure in patients without AF will add important information.
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      Linked Article

      • Randomized Trial of Surgical Left Atrial Appendage Closure: Protection Against Cerebrovascular Events
        Seminars in Thoracic and Cardiovascular Surgery
        • Preview
          Following open-heart surgery, atrial fibrillation and stroke occur frequently. Left atrial appendage closure added to elective open-heart surgery could reduce the risk of ischemic stroke. We aim to examine if routine closure of the left atrial appendage in patients undergoing open-heart surgery provides long-term protection against cerebrovascular events independently of atrial fibrillation history, stroke risk, and oral anticoagulation use. Long-term follow-up of patients enrolled in the prospective, randomized, open-label, blinded evaluation trial entitled left atrial appendage closure by surgery (NCT02378116).
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