ADULT – Original Submission|Articles in Press

A Retrospective Evaluation of Endo-aortic Balloon Occlusion Compared to External Clamping in Minimally Invasive Mitral Valve Surgery

      We compare outcomes of endo-aortic balloon occlusion (EABO) versus external aortic clamping (EAC) in patients undergoing minimally invasive mitral valve surgery (MIMVS) in the Society of Thoracic Surgeons (STS) Adult Cardiac Surgery Database. Adults undergoing mitral valve surgery (July 2017 – December 2018) were identified within the STS database (N=60,607). 7,978 patients underwent a minimally invasive approach (including robotically assisted). 1,163 EABO patients were 1:1 propensity-matched to EAC patients using exact matching on age, sex, and type of mitral procedure, and propensity-score average matching for 16 other risk indicators. Early outcomes were compared. Categorical variables were compared using logistic regression; hospital and intensive care unit (ICU) length of stay (LOS) were compared using negative binomial regression. In the matched cohort, mean age was 62 years; 35.9% were female, and 86% underwent mitral valve repair. Cardiopulmonary bypass time was shorter for EABO versus EAC group (125.0±53.0 vs 134.0 ±67.0 minutes, P=0.0009). There was one aortic dissection in the EAC group and none in the EABO group, (p-value>0.31), and no statistically significant differences in cross-clamp time, major intraoperative bleeding, perioperative mortality, stroke, new onset of atrial fibrillation, postoperative AKI, success of repair. Median hospital LOS was shorter for EABO versus EAC procedures (4 versus 5 days, P<0.0001). In this large, retrospective, STS database propensity matched analysis of patients undergoing MIMVS, we observed similar safety outcomes for EABO and EAC, including no aortic dissections in the EABO group. The EABO group showed slightly shorter CPB times and hospital LOS.

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      AKI (acute kidney injury), CPB (cardiopulmonary bypass), EABO (endo-aortic balloon occlusion), EAC (external aortic clamping), GLM (generalized linear modeling), ICU (intensive care unit), IRR (incident rate ratio), LOS (length of stay), MI (myocardial infarction), MIMVS (minimally invasive mitral valve surgery), MR (mitral regurgitation), STS (Society of Thoracic Surgeons), TIA (transient ischemic attack)
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